New Diet Pill


To meet the growing demand for prescription and non-prescription weight loss products, pharmaceutical companies invest millions of $ in the development and research of new diet pills. Note that the new diet pill can be called only one that contains an innovative active ingredient or a unique combination of different active ingredients. As an exception, the new diet pill can be called the pill, which has a unique dosage form. For example, usual diet pills containing Phentermine have been sold in the USA for over 50 years.

The first Phentermine chewable diet pill went on sale in 2012. The new chewing diet pill is sold at the US pharmacies under the brand Suprenza. The advantage of new Suprenza (Phentermine) diet pill over usual Phentermine pills is that the chewable pills dissolve in the mouth in just a few seconds. The diet pill cannot be called the new one if its generic versions containing the same active ingredient are available in retail sale. For instance, in the late 90s of the last century, Orlistat pills first became available in the UK.

More than 10 years, Orlistat slimming drug was sold only under the brands Xenical and Alli in the UK. In 2012, other Orlistat-containing drugs including Beacita slimming drug became available at the UK pharmacies. In 2012, many consumers of weight loss products called Beacita the new diet pills. However, for professionals, Beacita drug was just a generic version of Alli and Xenical. In 2012, “the new” Beacita diet pill was cheaper than Xenical or Alli diet pills. For several years, Xenical and Alli prices gradually decreased in the UK. Therefore, today, the price of “new” Beacita diet pill in the UK is comparable to the price of other Orlistat-containing drugs, Alli as well.

To develop a new diet pill, it is required not only a lot of money, but also much time. The duration of creating a new diet pill can reach several decades. However, even successful clinical studies cannot guarantee a long-term safety of the new diet pill. Over the past 55 years, the sales of more than 20 new diet pills were launched in the USA. Some of the new diet drugs were withdrawn in just a few years after the start of sales. For example, in 2006, Sanofi company received the European marketing authorization for Rimonabant diet pill. In the UK, the new Rimonabant diet pills were sold under the brand Acomplia.

Two years after the beginning of sales of the new diet pill, the European Medicines Agency (EMA) published a warning about the fact that Acomplia can cause severe psychiatric side effects. In 2008, the EMA recommended suspending the sales of Acomplia and in 2009 Sanofi voluntarily withdrew Acomplia from the international pharmaceutical market. The similar case happened with a relatively “new” diet pill – Meridia (Sibutramine) approved by the FDA in 1999. A little more than 10 years, Meridia pills were sold at the US pharmacies. However, because of Meridia ability to cause severe cardiovascular side effects, these diet pills were withdrawn from the US market and their retail sale was discontinued in 2010.

After the recall of Acomplia and Meridia, the only “new” prescription diet drug – Orlistat first approved by the FDA in April 1999, remained at the market. A new stage of development of the global market of weight loss products began in 2012.

Two years after Meridia recall, the launch of sales of two new diet drugs was announced in the USA.

  • In June 2012, the FDA approved a new diet pill – Belviq
  • In July 2012, the FDA approved a new diet pill – Qsymia

Belviq is the fundamentally new diet pill containing the innovative active substance Lorcaserin. Belviq is the first serotonergic anorectic approved by the FDA as a short-term treatment of obesity. The new diet pill – Qsymia is different from Belviq by that contains two active substances: Phentermine and Topiramate. Drug containing only Phentermine first was approved by the FDA in 1959, as well as first went on sale under the brand Ionamin.

  • Drug containing only Topiramate first was approved by the FDA in 1969 and first launched on the market under the brand Topamax.

The new diet pill – Qsymia (with Topiramate and Phentermine) is a unique weight loss product. In 2015, Qsymia combined diet pills have no analogs. Herewith, patent protection for Qsymia (Phentermine; Topiramate) in the U.S. was expected to expire in 2020. During the next 5 years, diet pills with Topiramate and Phentermine will be sold under the brand Qsymia. Another combined diet drug is sold under the brand Contrave in the USA.

Just as Qsymia, the new diet pill – Contrave contains two active ingredients Bupropion and Naltrexone.

  • Naltrexone-containing drug first was approved by the FDA in 1984 and in 2015 and sold under different trade names, Revia included.
  • Since December 1985, Bupropion-containing drug has been sold in the USA under the brand Wellbutrin.

In 2015, the new diet pill with Bupropion and Naltrexone – Contrave is sold only in the USA. In the UK and EU, Contrave generic sold at pharmacies under the brand name Mysimba is approved for the obesity treatment.

The newest diet pills – Qsymia, Contrave and Belviq can cause side effects, so are sold by prescription only. The new diet drugs are also available at the market of over the counter weight loss products. Therefore, those, who have contraindications to Belviq, Qsymia and Contrave, can find the suppliers of best weight loss supplements that sell the new diet pills without a prescription. Information on new OTC or RX diet pill can be found on online magazines, newspapers, blogs, forums and reviews of weight loss products consumers. In July 2015, a popular newspaper in the UK and the USA – the Daily Mail published a review of a new diet pill – Slim Fizz.

The review states that the new diet pills – Slim Fizz are available on Amazon. However, at time of the publication of this review (“New diet pills”), Slim Fizz pills have not been sold on Amazon, GNC and other online retailers of weight loss products.

What if you could trick your body into thinking you’d eaten? Scientists at the Salk Institute for Biological Studies in La Jolla, California, may have stumbled upon this holy grail of diet pills.The pill, called fexaramine, led to fat loss and weight loss, improved blood sugar and cholesterol, and lowered inflammation in mice. The rodents’ body temperature rose, indicating a higher metabolism, and some of their white fat deposits turned into healthier, energy-burning brown fat cells. “The mice lost more than 10% of their body weight in 5 weeks,” says lead researcher Ronald Evans, PhD, director of the Gene Expression Laboratory at the Salk Institute.
 The secret to the pill’s success lies in its ability to trip sensors in the body that signal fullness after a meal. “The very first thing that happens when you eat is the release of a substance called bile acid in your intestine that helps to digest food,” Evans explains. The bile acid then kicks off a series of events in the body. “It’s like a relay race with a baton getting passed—bile activates the liver, blood flow increases, and fat tissue burns some calories to make room for new ones, except there are no new calories,” he says. Without the expected payload, fat cells give up their fuel and get smaller.
Fexaramine respects nature—it doesn’t even try to stop you from scarfing cheeseburgers. “Eating is genetically programmed for survival,” Evans says. “You can develop drugs to suppress appetite, but you’re trying to block an evolutionary instinct, which causes all sorts of counter responses in the body to keep you eating.” Instead, fexaramine stimulates a natural function—the digestion process, which is a job the body is happy to perform.

Fexaramine may also prove to be safer than many diet drugs because it never hits the blood stream; it works only on the intestine, where digestion begins. He’s hopeful that with the pill’s high safety profile and impressive results—doubling the FDA’s requirement that a weight loss drug cause 5% body weight over a year—fexaramine it will jump the hurdles of development and approval quickly, possibly within two years.

Because people manage their weight a little differently than mice, we can’t yet say that the benefit will translate,” Evans says. “But the sensor is the same and the system is the same, so we have a lot of enthusiasm.”

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